| Item Type | Name |
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Concept
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Cyclic AMP Response Element-Binding Protein
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Concept
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Myeloid Differentiation Factor 88
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Concept
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Insulin-Like Growth Factor I
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Concept
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Iron-Binding Proteins
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Concept
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Monomeric GTP-Binding Proteins
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Concept
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Insulin Resistance
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Concept
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Insulin-Secreting Cells
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Concept
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Receptor, Insulin
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Concept
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Time Factors
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Concept
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Insulin
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Concept
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Basic Helix-Loop-Helix Transcription Factors
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Concept
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Age Factors
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Concept
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Octamer Transcription Factor-1
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Concept
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Insulin Receptor Substrate Proteins
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Concept
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Forkhead Transcription Factors
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Concept
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Transcription Factors
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Concept
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Risk Factors
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Academic Article
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PAS kinase is required for normal cellular energy balance.
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Academic Article
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A role for the transcriptional coactivator PGC-1alpha in muscle refueling.
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Academic Article
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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans.
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Academic Article
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Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity.
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Academic Article
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Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase.
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Academic Article
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Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis.
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Academic Article
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Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus.
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Academic Article
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Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.
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Academic Article
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MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.
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Academic Article
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Adipocyte iron regulates adiponectin and insulin sensitivity.
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Academic Article
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Hyperglycemia and inhibition of glycogen synthase in streptozotocin-treated mice: role of O-linked N-acetylglucosamine.
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Academic Article
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Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism.
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Academic Article
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Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.
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Academic Article
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Oxidative stress, beta-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis.
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Academic Article
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Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.
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Academic Article
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Manganese supplementation protects against diet-induced diabetes in wild type mice by enhancing insulin secretion.
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Academic Article
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Adipocytes with increased hexosamine flux exhibit insulin resistance, increased glucose uptake, and increased synthesis and storage of lipid.
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Academic Article
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Iron and diabetes risk.
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Academic Article
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Dietary iron restriction or iron chelation protects from diabetes and loss of beta-cell function in the obese (ob/ob lep-/-) mouse.
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Academic Article
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The role of mPer2 clock gene in glucocorticoid and feeding rhythms.
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Academic Article
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Increased strength and physical performance with eccentric training in women with impaired glucose tolerance: a pilot study.
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Academic Article
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Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.
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Academic Article
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Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1a.
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Academic Article
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Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.
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Academic Article
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Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway.
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Academic Article
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Hexosamines regulate sensitivity of glucose-stimulated insulin secretion in beta-cells.
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Academic Article
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Iron overload and diabetes risk: a shift from glucose to Fatty Acid oxidation and increased hepatic glucose production in a mouse model of hereditary hemochromatosis.
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Academic Article
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Muscle damage and muscle remodeling: no pain, no gain?
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Academic Article
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Downregulation of E3 ubiquitin ligases and mitophagy-related genes in skeletal muscle of physically inactive, frail older women: a cross-sectional comparison.
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Academic Article
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Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic ß-cell function and vascularization.
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Academic Article
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Anti-obesity and pro-diabetic effects of hemochromatosis.
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Academic Article
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Skeletal muscle Ras-related GTP binding B mRNA and protein expression is increased after essential amino acid ingestion in healthy humans.
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Academic Article
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Hexosamines as mediators of nutrient sensing and regulation in diabetes.
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Academic Article
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Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.
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Academic Article
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A genetic mechanism for Tibetan high-altitude adaptation.
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Academic Article
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Transgenic mice overexpressing the rate-limiting enzyme for hexosamine synthesis in skeletal muscle or adipose tissue exhibit total body insulin resistance.
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Academic Article
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Dietary iron controls circadian hepatic glucose metabolism through heme synthesis.
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Academic Article
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Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia.
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Academic Article
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Genetic determinants of Tibetan high-altitude adaptation.
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Academic Article
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Recipes for creating animal models of diabetic cardiovascular disease.
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Academic Article
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Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.
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Academic Article
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MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.
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Academic Article
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Adipocyte iron regulates leptin and food intake.
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Academic Article
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Mechanisms Linking Glucose Homeostasis and Iron Metabolism Toward the Onset and Progression of Type 2 Diabetes.
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Academic Article
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Metabolic aspects of high-altitude adaptation in Tibetans.
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Grant
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Iron reduction by phlebotomy for the prevention and treatment of type 2 diabetes
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Grant
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University of Utah Center for Clinical and Translational Science-UL1
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Grant
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Iron And Metabolism: Altered Fuel Oxidation And Mitochondrial Dysfunction
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Grant
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Hexosamines, Glucose Toxicity and Insulin Resistance
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Grant
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University of Utah Center for Clinical and Translational Science-UL1
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Grant
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DIABETES IN HEMOCHROMATOSIS: PREVALENCE AND MECHANISMS
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Grant
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ALTERNATE FORMS OF THE INSULIN RECEPTOR
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Grant
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Iron, the circadian clock, and diabetes risk
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Grant
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Diabetes in Hemochromatosis: Prevalence and Mechanisms
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Academic Article
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Adipose Tissue Transferrin and Insulin Resistance.
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Grant
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Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver Disease
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Academic Article
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Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance.
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Academic Article
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Iron down-regulates leptin by suppressing protein O-GlcNAc modification in adipocytes, resulting in decreased levels of O-glycosylated CREB.
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Academic Article
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Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness.
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Grant
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Mechanism of Integrative Metabolic Regulation by Iron and Hypoxia
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